The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers Cooper Kupp and Puka Nacua.

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

The Niners will perhaps be without arguably their three most important offensive weapons, sidelined stars Christian McCaffrey ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

After an encouraging performance in Week 1, the Rams (0-2) got something of a wake-up call in the 41-10 loss to the Cardinals ...

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George Kittle and Charvarius Ward both missed practice Thursday, three days shy of the 49ers’ visit to Los Angeles where they ...

Vikings star wide receiver Justin Jefferson was forced out of the game late in the third quarter against San Francisco with a ...

Asked this week about facing an 0-2 Los Angeles Rams team that fell 41-10 to the Arizona Cardinals on Sunday, Kyle Shanahan ...

The Los Angeles Rams need top draft picks Jared Verse and Braden Fiske to come up big Sunday against a 49ers’ squad that ...

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

New KNBR program director Mike Hohler didn't think he was built for the job for years. But now, he's set to lead the station ...