How did life come about? The answer to this question goes to the very heart of our existence on planet Earth. Did life simply arise from chemical reactions among organic compounds in a primordial soup ...
After encountering foreign antigen, B cells diversify their immunoglobulin genes by somatic hypermutation (SHM), gene conversion (GC) and class-switch recombination (CSR). SHM introduces mutations ...
Samples from the asteroid Ryugu collected by the Hayabusa2 mission contain nitrogenous organic compounds, including the nucleobase uracil, which is a part of RNA. Researchers have analyzed samples of ...
Back in 2010, Japan’s space agency JAXA completed one of the biggest milestones in the history of space exploration: It collected samples from an asteroid and brought them back to Earth. A decade ...
April 21, 2004 — Adjuvant chemotherapy with uracil and tegafur (UFT) improves survival of patients with completely resected pathological stage I adenocarcinoma of the lung, according to the results of ...
In a previous phase 3 trial of adjuvant chemotherapy after resection of non–small-cell lung cancer, a combination of uracil and tegafur (often referred to as UFT) taken orally was shown to prolong ...
Preoperative Therapy With Trastuzumab and Paclitaxel Followed by Sequential Adjuvant Doxorubicin/Cyclophosphamide for HER2 Overexpressing Stage II or III Breast ...
Between October 1996 and April 2001, a total of 733 patients were randomly assigned to receive either treatment. The median follow-up time was 6.2 years. The RFS rates at 5 years were 88.0% in the CMF ...
Protein p56 encoded by the Bacillus subtilis phage φ29 inhibits host uracil-DNA glycosylase (UDG) activity. In previous studies, we suggested that this inhibition is likely a defense mechanism ...
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