A team has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new means ...

Chimeric antigen receptor-T cell (CAR-T cell) therapies have been a significant advance in the field of cancer immunotherapeutics in recent years, particularly for B-cell malignancies. Yet, this ...

PURPOSE: The expression of the carcinoma-associated mucin MUC-1 is thought to be restricted to epithelial cells and is used for micrometastatic tumor cell detection in patients with solid tumors, ...

Researchers reveal how bone marrow fat reprograms immune signaling to promote osteoclast activity and weaken bones ...

Bone marrow is the soft, fatty center of some bones in the body. It contains stem cells that become various blood and immune cells, including red blood cells, white blood cells, and platelets. Each of ...