With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the ...

New research has shown that the enzyme OTULIN regulates tau at the gene-expression level rather than through protein ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia ...

The study combines a deep learning model with CRISPR screens to control the expression of human genes in different ways -- such as flicking a light switch to shut them off completely or by using a ...

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Researchers have created a battery-powered device that stimulates gene expression and prompts cells to produce insulin in diabetic mice, cracking open a door to a future where wearable electronics ...

“This suggests that longer-lived species may have evolved molecular programs that optimize splicing for longevity, allowing ...

A new study shows that RNA splicing, not just gene expression, holds powerful clues to why some mammals live far longer than ...