Labor onset is a complex process influenced by multiple factors. Although the mechanisms initiating labor remain incompletely understood, accumulating evidence suggests that maternal immune responses ...

A research group has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

A research group has discovered that certain naturally occurring peptides in the body can trigger contractions in the vas deferens—a muscular tube that carries sperm in the male reproductive system.

Because RyR1 is also expressed in neurons, immune cells, and vascular smooth muscle, the E3896A model offers a unique tool to examine CICR's broader physiological roles. By combining gene engineering, ...

Space exploration represents a frontier to understand how the human body adapts to extreme environments 1,2. Among the various specialties, microgravity exerts a persistent and substantial influence ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...