Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

Sequence analysis is a cornerstone of modern bioinformatics, encompassing the computational exploration of biological sequences—be they DNA, RNA or proteins—to reveal insights into structure, function ...

In bioinformatics, multiple sequence alignment (MSA) is an NP-hard problem. Nature-inspired approaches can provide an approximate solution compared to conventional approaches. In this article, the MSA ...

Subscribe to our newsletter for the latest sci-tech news updates. Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number ...

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

In a new article, researchers explain their work on computer-assisted approaches towards surveillance and consequent design of drugs and vaccines to combat the growth and spread of the Zika virus. The ...

A detailed examination of top-down proteomics and its critical role in comprehensive proteoform identification using advanced ...

Can I level with you? I’m not always sure I know what people are talking about when they say algorithm? You’re not alone: Honestly, I haven’t always been sure what I meant when I said it either. But ...