Kidney disease may trigger rare, potentially fatal brain virus, study says

A recent case study found a possible new trigger for a dangerous, and sometimes fatal, virus that could be laying dormant in ...

You’re likely already infected with a brain-eating virus you’ve never heard of

There’s a virus you may have never heard of before that is estimated to infect up to 90 percent of people and lurks quietly ...
MedPage Today

PML Not Fatal if Caught Early

SAN DIEGO – All multiple sclerosis patients taking natalizumab (Tysabri) who were diagnosed with progressive multifocal leukoencephalopathy (PML) before symptoms appeared were still alive a year later ...
Nature

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias

It has been shown that individual acute myeloid leukemia (AML) patients are characterized by one of few initiating DNA mutations and 5–10 cooperating mutations not yet defined among hundreds ...
Medscape

High Survival Rate With Natalizumab-Associated PML

May 31, 2011 — The prognosis of natalizumab (Tysabri; Biogen Idec)–associated progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis (MS) appears to be better than for ...
Nature

Pml is essential for multiple apoptotic pathways

APL is a distinct subtype of myeloid leukaemia that in almost 100% of cases is associated with chromosomal translocations involving the PML and retinoic acid receptor α (RARA) loci, leading to the ...