Enzymes are molecular machines that carry out the chemical reactions that sustain all life, an ability that has captured the attention of scientists like me. Consider muscle movement. Your body ...

Epistasis, the non-additive effect of mutations, can provide combinatorial improvements to enzyme activity that substantially exceed the gains from individual mutations. Yet the molecular mechanisms ...

Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical motion ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life—how enzymes are able ...