A new Cell study suggests that T cell exhaustion in tumors is driven in part by failed proteostasis, causing damaged and misfolded proteins to accumulate inside tumor-infiltrating lymphocytes. Restori ...
Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...
B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...
An often-ignored type of cell in the brain plays a dynamic and surprisingly complex role in our ability to process information, according to new research. An often-ignored type of cell in the brain ...
Dr. Zhao said several of RS3's proteins are involved in placing or removing phosphate groups from other proteins—a regulatory function that he and his colleagues suspect plays a part in coordinating ...
In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...
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