Selective plane illumination microscopy (SPIM) is a type of light sheet fluorescence microscopy (LSFM), which is one such 3D imaging technique employing a thin sheet of light to illuminate cleared ...

In this useful Tools & Resources article, the authors describe a new cryogenic light microscopy design and characterize its temperature and spatial stability. This compelling system avoids the ...

A team from The Hebrew University of Jerusalem has introduced a new method for megapixel-scale fluorescence microscopy through complex scattering media. This approach resolves high-resolution images ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

From overcoming classical optical limits to tracking single proteins in real time, super-resolution imaging continues to ...

A Simple Touchscreen Fluorescence Cell Imager Improves Workflow for Routine Applications Whether it’s for gaining a better understanding of how cells work, studying the effects of drugs or toxins on ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...